Description
Serum, NA, Fasting or Non Fasting: As suggested by doctor
Sample Required:
The HE4 serum test requires a blood sample. A trained healthcare professional will typically collect this sample by drawing blood from a vein in your arm.
Test Time:
The turnaround time for the HE4 test can vary depending on the laboratory or healthcare facility conducting the analysis. Results are usually available within a few days to a week.
Test Normal Range:
The normal range for HE4 levels can vary between different laboratories and may also depend on factors such as age and gender. Your healthcare provider will interpret your results and determine whether they fall within the expected range for your specific circumstances.
What is the Test?
The HE4 (Human Epididymis Protein 4) serum test is a blood test that measures the concentration of HE4 protein in the blood. Elevated levels of HE4 can be associated with certain types of ovarian cancer, particularly epithelial ovarian cancer (EOC).
Test Procedure:
A blood sample will be taken from a vein in your arm by a healthcare practitioner. After that, the blood sample is transported to a laboratory for analysis. Specialized equipment and techniques are used in the laboratory to determine the concentration of HE4 protein in the serum.
When to Take the Test:
As a tool for assessing the risk of ovarian cancer in women with pelvic masses or other symptoms. To monitor the progress of treatment for ovarian cancer. As a part of routine screening in individuals at high risk for ovarian cancer.
Who Should Take This Test:
Individuals who may benefit from the HE4 test include those with symptoms suggestive of ovarian cancer, those with a family history of ovarian cancer, and those with known risk factors for the disease. Your healthcare provider can recommend the test based on your individual circumstances.
Precautions for Exceptional Cases:
While pregnancy itself may not significantly affect HE4 levels, it’s essential to inform your healthcare provider if you are pregnant or planning to become pregnant before taking the test. Your healthcare provider will consider this information when interpreting your results.
FAQs (Frequently Asked Questions):
Q1: What is the significance of elevated HE4 levels?
A: Elevated HE4 levels can be associated with certain types of ovarian cancer, particularly epithelial ovarian cancer. However, elevated levels do not confirm the presence of cancer, and further evaluation is typically required.
Q2: Are there other factors that can cause elevated HE4 levels?
A: Yes, factors such as certain benign gynecological conditions and pelvic inflammatory disease can also lead to elevated HE4 levels. Therefore, the HE4 test is often used in combination with other tests and clinical evaluation.
Q3: Is the HE4 test used for ovarian cancer screening in the general population?
A: The HE4 test is not typically used for routine ovarian cancer screening in the general population. It is more commonly used in specific clinical situations, such as assessing the risk of ovarian cancer in women with symptoms or risk factors.
Q4: Can the HE4 test detect all types of ovarian cancer?
A: The HE4 test is most relevant for epithelial ovarian cancer (EOC), which is the most common type of ovarian cancer. It may not be as sensitive for detecting other, less common types of ovarian cancer.
Q5: What other tests are used in conjunction with the HE4 test for ovarian cancer diagnosis?
A: Ovarian cancer diagnosis usually involves a combination of tests, including the HE4 test, CA-125 blood test, pelvic imaging (e.g., ultrasound), and clinical evaluation. The specific tests used may vary based on individual circumstances and clinical judgment.
