Description
Ds DNA, Nucleosomes, Histones, SS-A, RO-52, SS-B, RNP/SM, SM, MI-2A, M1-2B, KU, CENPA, CENP B,SP100 PML, Scl-70, PM100, PM75,
RP11,RP155, GP210, PCNA, DFS70
Sample Type:Serum
Tests Included:
ENA5 is a test that checks for specific antibodies that target a group of 23 different antigens present in the cell nucleus. These antigens are associated with autoimmune diseases like lupus (SLE), mixed connective tissue disease, or Sjogren’s syndrome.
Sample Required:
Blood sample.
Test Time:
Results might be available within a few days to a week, depending on the specific antigens tested and laboratory processing.
Test Range Values:
Results are interpreted based on the presence or absence of specific antibodies against the antigens tested.
What is the test?
The ENA5 test evaluates the presence of specific antibodies targeting a range of nuclear antigens, aiding in the diagnosis of autoimmune diseases.
Test Procedure:
Blood samples are collected and analyzed in the laboratory to detect antibodies against the specific antigens.
When to take the test:
It’s ordered when autoimmune diseases such as lupus, mixed connective tissue disease, or Sjogren’s syndrome are suspected based on symptoms or clinical findings.
Who should take the test:
Individuals showing symptoms or signs suggestive of autoimmune diseases, or those requiring confirmation of a diagnosis might need this test.
Precautions for exceptional cases (if any):
Discuss any symptoms or specific concerns with the healthcare provider.
Frequently Asked Questions (FAQs) for ENA5 (23 Antigens) Test:
Q1: Why are specific antigens tested in the ENA5 panel?
A: These antigens are associated with various autoimmune diseases, and their antibodies aid in diagnosing conditions like lupus or mixed connective tissue disease.
Q2: Can this test definitively confirm autoimmune diseases?
A: It contributes to the diagnosis, but clinical correlation and further tests might be needed for confirmation.
Q3: What conditions are associated with the presence of these antigens?
A: Lupus (SLE), mixed connective tissue disease, Sjogren’s syndrome, and other autoimmune conditions might involve these antigens.
Q4: Are lifestyle factors relevant to this test’s results?
A: Lifestyle factors might not directly affect these specific tests, but overall health might impact disease presentation.
Q5: How often should individuals with known autoimmune conditions undergo monitoring?
A: Frequency depends on individual health status, treatment plan, and healthcare provider recommendations. Regular monitoring might be necessary for some.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
