Description
Anti Tissue Transglutaminase IgG
Sample Type:Serum
Tests Included:
Measurement of Anti-Tissue Transglutaminase IgG antibodies
Sample Required:
Blood sample
Test Time:
Results are typically available within a few days.
Test Range Values:
Normal values usually range below 7 U/mL. However, specific reference ranges might vary between laboratories.
What is the test?
This test measures the presence of IgG antibodies against tissue transglutaminase, a key marker for diagnosing certain autoimmune conditions like celiac disease.
Test Procedure:
A blood sample is collected from a vein, and the concentration of Anti-Tissue Transglutaminase IgG antibodies is assessed in the laboratory.
When to take the test:
It’s recommended for individuals suspected of having celiac disease or related autoimmune conditions, especially when other tests, symptoms, or family history suggest gluten sensitivity.
Who should take the test:
Individuals experiencing symptoms such as chronic diarrhea, abdominal pain, anemia, or other signs associated with celiac disease or related autoimmune disorders may require this test.
Precautions for exceptional cases (pregnancy, etc.):
This test is generally safe for most individuals. Pregnant individuals should inform their healthcare provider about their pregnancy status, as it may impact the interpretation of results.
Frequently Asked Questions (FAQs) for Anti-Tissue Transglutaminase IgG Test:
Q1: How accurate is the Anti-Tissue Transglutaminase IgG test in diagnosing celiac disease?
A: The Anti-Tissue Transglutaminase IgG test is highly specific for celiac disease and is often used as a primary screening tool due to its accuracy in detecting antibodies associated with the condition.
Q2: Can this test detect gluten sensitivity even if celiac disease is not present?
A: Yes, elevated levels of Anti-Tissue Transglutaminase IgG antibodies might indicate gluten sensitivity or non-celiac gluten sensitivity, warranting further investigation.
Q3: Are there any medications or conditions that could affect the results of this test?
A: Some medications and certain conditions might interfere with test results. It’s essential to inform your healthcare provider about all medications and medical conditions before the test.
Q4: Can someone with a gluten-free diet still have a positive Anti-Tissue Transglutaminase IgG test?
A: In some cases, individuals on a gluten-free diet might have reduced antibody levels, leading to a negative test result even if they have celiac disease. Consult a healthcare professional for appropriate testing guidance.
Q5: Is there a need for additional tests if the Anti-Tissue Transglutaminase IgG result is positive?
A: Confirmatory tests, such as endoscopic biopsies, might be recommended to validate the diagnosis, especially if there’s a strong clinical suspicion of celiac disease despite the test results.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
