Description
C1 Esterase Inhibitor
Sample Type:Serum
Tests Included:
C1 Esterase Inhibitor measurement
Sample Required:
Blood sample
Test Time:
Results are typically available within a few days.
Test Range Values:
Normal levels of C1 Esterase Inhibitor in the blood are generally between 21 and 39 milligrams per deciliter (mg/dL).
What is the test?
The C1 Esterase Inhibitor test measures the level of C1 inhibitor, a protein that helps regulate the complement system involved in immune responses.
Test Procedure:
A blood sample is drawn from a vein, and the concentration of C1 Esterase Inhibitor is measured in the laboratory.
When to take the test:
The test is recommended to evaluate and monitor hereditary angioedema (HAE) or acquired angioedema (AAE).
Who should take the test:
Patients with symptoms of hereditary or acquired angioedema, or those with a family history of HAE might require this test. It’s usually ordered by allergists, immunologists, or hematologists.
Precautions for exceptional cases (pregnancy, etc.):
C1 Esterase Inhibitor levels might be influenced by pregnancy, but there are no specific precautions related to this test during pregnancy.
Frequently Asked Questions (FAQs) for C1 Esterase Inhibitor Test:
Q1: What is the role of C1 Esterase Inhibitor in the body?
A: C1 Esterase Inhibitor regulates the complement system, preventing excessive activation and helping control inflammation.
Q2: How does low C1 Esterase Inhibitor lead to angioedema?
A: Reduced levels or dysfunction of C1 Esterase Inhibitor can lead to uncontrolled activation of the complement system, causing swelling and angioedema.
Q3: Can medications impact C1 Esterase Inhibitor levels?
A: Some medications might influence C1 Esterase Inhibitor levels, but the specific effects vary. Discuss medication use with healthcare providers before the test.
Q4: Is the C1 Esterase Inhibitor test definitive for diagnosing angioedema?
A: While the test helps in diagnosing certain types of angioedema, additional clinical evaluations and tests are often required for a definitive diagnosis.
Q5: Can stress or lifestyle factors affect C1 Esterase Inhibitor levels?
A: Stress and lifestyle factors typically do not significantly affect C1 Esterase Inhibitor levels. However, maintaining overall health might positively impact immune function and responses.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
