Description
Cortisol (pm) (post dextamethozone
1mg of midnight)
Sample Type:Serum
Sample Required:
Blood sample (usually collected in the afternoon or evening)
Test Time:
Results typically available within a few days.
What is the test?
This test measures cortisol levels in the afternoon or evening after the administration of dexamethasone at midnight. It’s used to assess the body’s response to the medication and helps diagnose conditions related to cortisol regulation, such as Cushing’s syndrome or adrenal insufficiency.
Test Procedure:
A blood sample is drawn in the afternoon or evening following dexamethasone administration, and cortisol levels are measured in the laboratory.
When to take the test:
When evaluating cortisol regulation or diagnosing conditions related to cortisol production, such as Cushing’s syndrome or adrenal insufficiency.
Who should take the test:
Individuals with suspected adrenal disorders, Cushing’s syndrome, or those with unexplained changes in cortisol levels might undergo this test.
Precautions for exceptional cases (pregnancy, etc.):
Pregnant individuals might experience altered cortisol levels, and healthcare providers should consider this when interpreting results.
Frequently Asked Questions (FAQs) for Cortisol (pm) Test (post dexamethasone administration):
Q1: Why is dexamethasone given at midnight before the test?
A: Dexamethasone is a synthetic steroid that suppresses cortisol production. Administering it at midnight helps assess the body’s response to suppression.
Q2: What conditions can abnormal results indicate?
A: Failure to suppress cortisol levels after dexamethasone might indicate conditions like Cushing’s syndrome, while low cortisol levels might suggest adrenal insufficiency.
Q3: Can factors like stress affect the test results?
A: Yes, stress and certain medications or health conditions can influence cortisol levels, potentially affecting test results.
Q4: How are abnormal cortisol suppression test results treated?
A: Treatment depends on the underlying cause. It might involve medication adjustments or surgical interventions, depending on the specific condition.
Q5: Can food or drink affect cortisol levels in the evening?
A: Generally, food and drink don’t significantly affect evening cortisol levels unless there’s a specific condition affecting cortisol regulation.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
