Description
Endomysial Abs IgA Anti Gliadin IgA & lgG,
Anti Tissue Transglutaminase IgA & Immunoglobulin A
DQ2/DQ8
Sample Type:Whole Blood,Serum
Tests Included:
This profile typically includes antibody tests like anti-tissue transglutaminase antibodies (tTG-IgA), anti-endomysial antibodies (EMA-IgA), total IgA levels, and sometimes deamidated gliadin peptide (DGP) antibodies. It might also involve genetic testing for HLA-DQ2 and HLA-DQ8 genes associated with coeliac disease.
Sample Required:
Blood sample.
Test Time:
Results might be available within a few days to a week.
Test Range Values:
Results are interpreted based on the presence or absence of specific antibodies or genetic markers associated with coeliac disease.
What is the test?
The Gluten Sensitivity Evaluation/Coeliac Disease Profile helps diagnose coeliac disease by detecting antibodies or genetic markers associated with gluten intolerance or sensitivity.
Test Procedure:
Blood samples are collected and analyzed in the laboratory to detect antibodies or genetic markers.
When to take the test:
It’s ordered when assessing suspected coeliac disease based on symptoms like diarrhea, weight loss, bloating, or when there’s a family history of the condition.
Who should take the test:
Individuals exhibiting symptoms suggestive of coeliac disease or those at risk due to family history might require this profile.
Precautions for exceptional cases (if any):
The accuracy of the tests might be affected if individuals are already on a gluten-free diet. Consult the healthcare provider for specific instructions.
Frequently Asked Questions (FAQs) for Gluten Sensitivity Evaluation/Coeliac Disease Profile:
Q1: What do positive antibody results indicate in this profile?
A: Positive results suggest the presence of antibodies associated with coeliac disease, indicating gluten intolerance or sensitivity.
Q2: Is genetic testing necessary for diagnosing coeliac disease?
A: While not mandatory, genetic testing identifies the presence of genes associated with an increased risk for coeliac disease (HLA-DQ2 and HLA-DQ8), complementing antibody tests.
Q3: Can this profile differentiate between gluten sensitivity and coeliac disease?
A: Yes, it helps distinguish between gluten sensitivity and coeliac disease based on antibody and genetic marker presence.
Q4: How does this profile relate to other conditions with similar symptoms?
A: Coeliac disease symptoms can overlap with other gastrointestinal conditions, but specific antibody and genetic markers distinguish it from other disorders.
Q5: Is there a need for follow-up testing after a positive result?
A: Further evaluation by a gastroenterologist or specialist might include an intestinal biopsy to confirm coeliac disease if antibody tests or genetic markers are positive.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
