Description
Mixing Studies PTT
Sample Type:
Tests Included:
Mixing patient plasma with normal plasma to determine if a clotting factor deficiency or the presence of an inhibitor is causing the prolonged PTT.
Sample Required:
Blood sample.
Test Time:
Results are usually available within a few days.
What is the test?
Mixing Studies PTT is a laboratory test performed to investigate the cause of prolonged activated partial thromboplastin time (PTT), a test that measures how long it takes for blood to clot.
Test Procedure:
Patient plasma is mixed with normal plasma, and the PTT is measured before and after the mixing to determine whether a clotting factor deficiency or an inhibitor is causing the prolonged PTT.
Test Range Values:
Results are interpreted based on the change in PTT after mixing patient plasma with normal plasma.
When to Take the Test:
When there is a prolonged PTT identified in routine coagulation tests, to determine the cause of the clotting abnormality.
Who Should Take the Test:
Patients with suspected clotting factor deficiencies or those showing signs of prolonged PTT in routine coagulation tests.
Frequently Asked Questions (FAQs) for Mixing Studies PTT:
Q1: How does Mixing Studies PTT differ from a regular PTT test?
A: A regular PTT test measures the time it takes for blood to clot, while Mixing Studies PTT involves mixing patient plasma with normal plasma to diagnose clotting factor deficiencies or inhibitors.
Q2: Can Mixing Studies PTT identify specific clotting factor deficiencies?
A: Yes, it can help determine if a clotting factor deficiency is the cause of the prolonged PTT and may provide insights into which specific clotting factor(s) are affected.
Q3: Are there conditions that can cause false-positive results in Mixing Studies PTT?
A: Certain conditions like lupus anticoagulant or presence of heparin can interfere with Mixing Studies PTT and lead to false-positive results.
Q4: What if the PTT corrects after mixing patient and normal plasma samples?
A: If the PTT corrects after mixing, it suggests that a clotting factor deficiency is causing the prolonged PTT rather than the presence of inhibitors.
Q5: Can Mixing Studies PTT results help guide treatment decisions?
A: Yes, identifying the cause of prolonged PTT through Mixing Studies can assist healthcare providers in determining appropriate treatment strategies for clotting abnormalities.
*Please note that specific testing protocols and guidelines may vary based on the latest recommendations from health authorities and regulatory agencies. It is essential to consult healthcare professionals and follow local testing guidelines for accurate and appropriate testing.
