Description
Serum, NA, Fasting or Non Fasting: As suggested by doctor
Sample Required:
The test requires a blood sample.
Test Time:
Test results are typically available within a few hours to a day.
Test Normal Range:
The normal range for C1 esterase inhibitor levels can vary depending on the laboratory’s reference values.
What is the Test?
The C1 esterase inhibitor test measures the level of C1 esterase inhibitor in the blood. C1 esterase inhibitor is a protein that helps regulate the complement system, a part of the immune system. Low levels of this protein can lead to hereditary angioedema (HAE) or acquired angioedema (AAE), which are conditions characterized by swelling of various body parts.
Test Procedure:
Blood Collection: A blood sample is drawn from a vein, usually from the arm.Laboratory Analysis: The blood sample is sent to a laboratory for analysis to measure the level of C1 esterase inhibitor.
When to Take the Test:
This test is taken when there is a suspicion of hereditary or acquired angioedema due to unexplained episodes of swelling.
Who Should Take This Test:
Individuals with recurrent episodes of unexplained swelling, especially around the face, limbs, or genitalia. People with a family history of hereditary angioedema. Those suspected of having acquired angioedema
Precautions for Exceptional Cases (Pregnancy etc.):
Pregnant individuals should inform their healthcare provider about their pregnancy status before taking the test, as some precautions might be necessary.
FAQs:
Q1: What is the role of C1 esterase inhibitor in the body?
A: C1 esterase inhibitor regulates the complement system to prevent excessive inflammation and swelling in response to triggers.
Q2: What are the symptoms of hereditary angioedema?
A: Symptoms include sudden and severe swelling of the skin, mucous membranes, and submucosal tissues, often causing pain and discomfort.
Q3: How is acquired angioedema different from hereditary angioedema?
A: Acquired angioedema is not hereditary but is caused by the immune system attacking its own tissues. Hereditary angioedema is genetic and runs in families.
Q4: Can stress trigger angioedema episodes?
A: Yes, stress can potentially trigger angioedema episodes in some individuals. However, there are various triggers, and each case is unique.
Q5: How is angioedema treated?
A: Treatment may involve medications to manage symptoms and prevent attacks, as well as strategies to identify and avoid triggers. Consult a healthcare provider for personalized guidance.
