Serum, NA, Fasting or Non Fasting: As suggested by doctor
For the 5-Hydroxy Indole Acetic Acid (5-HIAA) test, a 24-hour urine sample is required. This means that all urine produced over a 24-hour period is collected for the test.
The collection of the 24-hour urine sample takes a full day. Once the sample is collected, it is sent to a laboratory for analysis. The results are typically available within a few days.
Test Normal Range:
The normal range for 5-HIAA levels in urine can vary based on factors such as age and diet. Generally, the normal range is up to 5 to 15 milligrams (mg) of 5-HIAA per 24 hours.
What is the Test?
The 5-Hydroxy Indole Acetic Acid (5-HIAA) test measures the level of 5-HIAA in urine. 5-HIAA is a breakdown product of serotonin, a neurotransmitter. The test is often used to diagnose and monitor certain types of tumors called carcinoid tumors, which can produce excess serotonin.
To perform the test, a healthcare provider will provide you with a container to collect all urine produced over a 24-hour period. This includes both day and night urine. After the collection period, the container is returned to the healthcare provider or laboratory for analysis.
When to Take the Test:
The test is often ordered if a person is suspected of having a carcinoid tumor or if there are symptoms such as flushing, diarrhea, or other signs of excessive serotonin production.
Who Should Take This Test:
Individuals with symptoms or signs suggestive of carcinoid tumors or excessive serotonin production may be advised to take this test.
Precautions for Exceptional Cases (Pregnancy, etc.):
Pregnant individuals or those with specific medical conditions should inform their healthcare provider before collecting the urine sample, as certain factors can influence the results.
Q1: What are carcinoid tumors?
A: Carcinoid tumors are a type of neuroendocrine tumor that can develop in various organs, including the gastrointestinal tract and lungs. They can produce hormones like serotonin and cause symptoms like flushing and diarrhea.
Q2: Can diet affect the results of the test?
A: Yes, certain foods like bananas, avocados, and pineapples can contain serotonin precursors and may affect the test results. It’s important to follow any dietary restrictions provided by your healthcare provider.
Q3: Is fasting required for this test?
A: Fasting is usually not required for the 5-HIAA test. However, your healthcare provider may provide specific instructions.
Q4: What is the significance of elevated 5-HIAA levels?
A: Elevated 5-HIAA levels may indicate the presence of a carcinoid tumor. Further tests and evaluations may be needed to confirm the diagnosis.
Q5: Can medications affect the test results?
A: Some medications, such as certain antidepressants, can affect serotonin metabolism and 5-HIAA levels. Inform your healthcare provider about any medications you are taking.