Description
Blood, Presence of HBcAg (core Antigen) in the cytoplasm and nucleus may reflect disease activity and predict response to antiviral treatment. Anti HBc IgM appears shortly after HBV infection and can be detected in serum soon after the appearance of circulating HBsAg and HBeAg. The levels are high during acute infection and typically disappear within 6 months, though it can persist in some cases of chronic hepatitis. Anti-HBc (IgG antibody) usually remains detectable for a lifetime. The Hepatitis B Core antigen test is used to detect hepatitis B virus (HBV) infection in an individual. This test also helps to assess the risk of re-infection/reactivation. Anti-HBc is the only serological marker that can detect HBV infection and potentially infectious blood. This test cannot differentiate between acute, chronic, and resolved HBV infection., Non Fasting
Sample Required:
The HBcAg IgM antibody test requires a blood sample, which is obtained by drawing blood from a vein in your arm.
Test Time:
The test results are typically available within a few hours to a few days, depending on the laboratory.
Test Normal Range:
The normal range for the HBcAg IgM antibody test is usually negative or non-reactive.
What is the test?
The HBcAg IgM antibody test is used to detect the presence of IgM antibodies against the hepatitis B core antigen (HBcAg) in the blood. It helps diagnose acute or recent hepatitis B virus (HBV) infection.
Test Procedure:
During the test, a blood sample is collected and analyzed in the laboratory. The presence of HBcAg IgM antibodies is determined using specific immunoassay techniques.
When to take the test?
The HBcAg IgM antibody test is typically performed when there is suspicion of acute or recent HBV infection. It is often ordered alongside other hepatitis B tests to confirm the diagnosis and assess the stage of infection.
Who should take this test?
Individuals who exhibit symptoms of acute hepatitis, such as fatigue, loss of appetite, jaundice (yellowing of the skin and eyes), dark urine, and abdominal pain, may be recommended to take the HBcAg IgM antibody test. It is also useful for those who have had recent exposure to HBV, such as through unprotected sexual contact or needle sharing.
Precautions for exceptional cases (pregnancy etc.):
If you are pregnant or have any other medical conditions, it is important to inform your healthcare provider before undergoing the HBcAg IgM antibody test. They will provide specific instructions or precautions based on your individual situation.
FAQs for HBcAg IgM Antibody Test:
Q1: What does a positive HBcAg IgM antibody test mean?
A: A positive result indicates the presence of IgM antibodies against HBcAg, suggesting acute or recent HBV infection. It is important to follow up with further tests to confirm the diagnosis and determine the appropriate management.
Q2: Can the HBcAg IgM antibody test differentiate between acute and chronic hepatitis B?
A: No, the HBcAg IgM antibody test is primarily used to detect acute or recent HBV infection. It cannot differentiate between acute and chronic infection. Additional tests, such as HBsAg and anti-HBs, are needed to assess the stage of infection.
Q3: How long after exposure can the HBcAg IgM antibody test detect infection?
A: The HBcAg IgM antibody test is most reliable within the first 6 months after HBV exposure. It may not detect infection in individuals who have had HBV for an extended period.
Q4: Is the HBcAg IgM antibody test included in routine hepatitis B screening?
A: Routine hepatitis B screening typically includes tests for HBsAg and anti-HBs antibodies. The HBcAg IgM antibody test is specific to acute or recent HBV infection and may not be included in routine screening unless there are specific indications.
Q5: Can a negative HBcAg IgM antibody test rule out hepatitis B infection?
A: A negative result does not completely rule out hepatitis B infection. It may indicate the absence of acute or recent infection but does not rule out the possibility of past or chronic infection. Further testing may be required for a comprehensive evaluation.