Description
Serum, Unconjugated estriol (E3) is a form of estrogen, which is biologically active. It is exclusively produced during pregnancy, unlike other estrogens. Unconjugated Estriol test is included as part of triple marker and quadruple marker test for antenatal screening for monitoring fetal development and knowing the risk of pregnancy-related complications like premature labor or fetal distress. The level of unconjugated estriol rises during pregnancy, especially in the first trimester. Low levels of unconjugated estriol indicate Down and trisomy-18 syndromes, and neural tube defects. High levels of estriol are observed in cases of congenital adrenal hyperplasia. Take the benefit of free home collection at a much affordable price, Non Fasting
Sample Required:
A blood sample is required for the Estriol Unconjugated (E3) Test. This blood sample is typically obtained through standard venipuncture procedures from a vein in your arm.
Test Time:
The Estriol Unconjugated (E3) Test is usually processed within a few hours to a few days, and results are typically available accordingly.
Test Normal Range:
Normal estriol unconjugated levels can vary depending on factors such as age and sex. In adult non-pregnant females, the typical range is 0.1 to 0.8 nanograms per milliliter (ng/mL).
What is the Test?
The Estriol Unconjugated (E3) Test measures the concentration of unconjugated estriol in your blood. Estriol is one of the three main forms of estrogen produced by the placenta during pregnancy and, to a lesser extent, by the fetal liver.
Test Procedure:
A blood sample is taken from a vein in your arm by a healthcare worker. The blood sample is sent to a laboratory for analysis. In the lab, specialized equipment is used to measure the concentration of unconjugated estriol in your blood.
When to Take the Test:
The Estriol Unconjugated (E3) Test is primarily used during pregnancy, particularly in the second and third trimesters. It helps assess the health and development of the placenta and the fetus.
Who Should Take This Test:
This test is typically ordered for pregnant individuals as part of prenatal care. It can be particularly important in cases where there is a history of pregnancy complications, such as preterm birth or fetal growth restriction, or when monitoring the health of the placenta is necessary.
Precautions for Exceptional Cases (Pregnancy, etc.):
If you are pregnant, it’s essential to follow your healthcare provider’s recommendations regarding prenatal testing and monitoring. Discuss any concerns or questions about this test with your healthcare team.
FAQs (Frequently Asked Questions):
Q1: Why is estriol unconjugated (E3) important during pregnancy?
A: Estriol, particularly unconjugated estriol, is produced by the fetal liver and placenta. Monitoring E3 levels can provide valuable information about fetal well-being and placental function.
Q2: What does it mean if estriol levels are low during pregnancy?
A: Low estriol levels may indicate potential issues with fetal growth or placental function. More evaluation and monitoring may be required.
Q3: Can the E3 test predict the gender of the baby?
A: No, the E3 test is primarily used to assess fetal and placental health and does not provide information about the baby’s gender.
Q4: Are there any risks associated with the E3 test?
A: The E3 test is a routine blood test and is generally considered safe. The risks are minimal and similar to those associated with any blood draw.
Q5: How often is the E3 test performed during pregnancy?
A: The frequency of E3 testing during pregnancy can vary depending on individual circumstances and healthcare provider recommendations. It is often part of routine prenatal screening, typically performed in the second and third trimesters.
